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・ 2/8th Field Regiment (Australia)
・ 2-pounder gun
・ 2-Propanoyl-3-(4-isopropylphenyl)-tropane
・ 2-Pyridone
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・ 2-Pyrrolidone
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・ 2-sec-Butyl-4,5-dihydrothiazole
・ 2-sided
・ 2-step (breakdance move)
・ 2-step garage
・ 2-Succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase
・ 2-Tetralone
・ 2-Tone Entertainment
・ 2-transitive group
・ 2-Undecanone
・ 2-valued morphism
・ 2-Vinylpyridine
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2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase : ウィキペディア英語版
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, also known as SHCHC synthase, is encoded by the menH gene in ''E.coli'' and functions in the synthesis of vitamin K. The specific step in the synthetic pathway that SHCHC synthase catalyzes is the conversion of 5-enolpyruvoyl-6-hydroxy-2-succinylcyclohex-3-ene-1-carboxylate to (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate and pyruvate.
== Background ==
Vitamin K is a fat soluble vitamin known to aid in blood clotting. It is recommended that all newborns receive an injection of vitamin K in order to prevent excessive bleeding of the brain after birth. There are two major forms of vitamin K that occur naturally. Phylloquinone, also known as K1, is synthesized by plants and is the major form of vitamin K in the diet. Menaquinone, K2, includes a range of forms that are synthesized by bacteria in the gut.
Vitamin K is synthesized from the molecule chorismate in a nine step conversion process. SHCHC synthase catalyzes the third step in the process.〔van Oostende C, Widhalm JR, Furt F, Ducluzeau AL, Basset GJC (2011) Phylloquinone (Vitamin K1): function, enzymes and genes. in Advances in Botanical Research, eds Fabrice Rébeillé and Roland Douce, 59: 229-61, Academic Press (Amsterdam).〕

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